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Location:
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Beyoğlu district, Istanbul, Turkey directly on the Golden Horn waterfront
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Retreat Type:
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5-star luxury hotel, longevity clinic, and wellness sanctuary
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Recommended Stay:
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Minimum 2 nights; longer stays recommended for full program benefit
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Program Focus:
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Biological age optimization, sleep, detox, immunity, stress management
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Packages Available:
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6 Well+ Detox, 360° Longevity, Sleep Optimization, Detox, Immunity Support, Stress Management
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Starting From:
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Rooms from approx. €600/night (S$872); wellness programs priced separately
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Best For:
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Executives, founders, and high-performance professionals investing in long-term health
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- Rated 4.95/5 across 186 reviews; 9.9/10 on Expedia and Booking.com; 10/10 on TripAdvisor
- Part of the Paris Society Hotel Collection, managed by Ennismore (joint venture with Accor)
- Wellness and longevity programs clinically supported by the London Regenerative Institute (LRI)
- 3-Michelin-starred chef Thomas Bühner heads Taste by Aliée, the hotel's signature restaurant
- Spa treatments use Biologique Recherche and Augustinus Bader, two of the most respected names in skin and cellular health
- Featured in Global Traveler (2025) and Hospitality Net
Aliée Istanbul is not trying to be a generic spa hotel. It sits on the site of the Ottoman imperial shipyard, one of Istanbul's most historically significant locations, and it has been rebuilt as a place where longevity science, cultural depth, and serious hospitality all work together.
The wellness offering is built around a 4,000 square meter sanctuary across three levels. It includes a longevity clinic backed by the London Regenerative Institute, advanced recovery technology (cryotherapy, infrared, lymphatic flow systems, and neurofeedback), and a team of practitioners who can put together a program that matches what you actually need, not a generic package.
The programs address four common problems for high-performing professionals: chronic sleep disruption, accumulated stress and burnout, cellular ageing and metabolic decline, and immune system fatigue from sustained high output. Each program approaches these from multiple angles: biomarker screening, advanced therapies, and hands-on treatment rather than treating them with a single modality.
This is not a place you come to zone out. It is a place you come to reset with intention, with measurement, and with a clear structure. This is why science-led longevity retreats are becoming increasingly popular among professionals looking for structured recovery and long-term health support.

Well+ Detox Package
Best suited for: Guests new to longevity programs, or anyone looking for a daily recovery baseline during their stay
Duration: Per-stay basis (treatments can be spread across the stay or shared between guests)
What it includes:
- Daily breakfast
- Infrared therapy: 10 minutes
- Cryotherapy: 10 minutes
- Flow system (lymphatic activation): 10 minutes
- Vibroacoustic therapy: 20 minutes
- Russian Banya: 45 minutes
- De-stress massage: 60 minutes
What this means in practice: This package layers detox modalities across body heat, cold, lymphatic stimulation, and deep tissue in a sequence designed to support cellular clearance and nervous system downregulation. For many guests, it is the most accessible starting point and a solid daily recovery structure during a longer stay.
360° Longevity Program
Best suited for: Professionals who want a comprehensive measure of where they are biologically — and a structured intervention to improve it. Many executives are becoming more interested in how biological age and performance are connected over time.
Duration: 7 hours (single day, intensive)
What it includes:
- Smart health assessment (baseline biometrics)
- Consultation with a longevity expert
- Biohacking circuit Infrared sauna, Cryotherapy, Lymphatic Flow system
- Oxygen therapy
- IV NAD+ infusion
- Neurofeedback session
- Functional movement session
- Immersive Alpha Quartz massage
What this means in practice: This is the most comprehensive single-day program at Aliée. It is built around the idea that you cannot improve what you have not measured, so it starts with a full assessment, then moves through a layered sequence designed to support cellular function, cognitive clarity, and physical recovery. NAD+ IV therapy in particular has gained significant clinical attention for its role in cellular energy metabolism and may support recovery from sustained high output. This type of biological health screening helps identify patterns linked to stress, recovery, sleep quality, and long-term aging.
Sleep Optimization Program
Best suited for: Professionals whose sleep has been disrupted by work patterns, travel, or sustained stress and who want a structured approach to fixing it
Duration: 5.5 hours
What it includes:
- Sleep screening
- Brainwave monitoring
- Neurofeedback therapy
- Infrared sauna with light therapy
- IV therapy for sleep support
- Oxygen therapy
- Deep sleep wave vibroacoustic session
- De-stress signature massage
What this means in practice: Poor sleep is one of the most underestimated performance drains for senior professionals. This program combines brainwave analysis with neurofeedback, a technique used to help the brain shift into restorative patterns, alongside IV support and physical therapies. It is designed to help reprogram sleep architecture, not just provide a single night of rest.
Detox Program
Best suited for: Anyone coming off a period of high stress, irregular eating, travel, or sustained high alcohol and caffeine intake
Duration: 4 hours
What it includes:
- So Check health screening
- Nutrition consultation
- Infrared sauna
- Cryotherapy
- Lymphatic flow session
- IV Glutathione
- Traditional hammam treatment
What this means in practice: Glutathione IV is widely used in functional medicine to support liver detoxification and antioxidant activity. Combined with the thermal contrast of infrared and cryo and the lymphatic stimulation, this program is designed to accelerate the body's natural clearance mechanisms, particularly useful after periods of sustained high output.
Immunity Support Program
Best suited for: Frequent travellers, professionals who have been ill recently, or anyone whose energy levels have been noticeably lower than baseline
Duration: 4.5 hours
What it includes:
- So Check health screening
- Cardiovascular assessment
- Infrared sauna
- Cryotherapy
- Oxygen therapy
- IV Immune Boost
- Vibroacoustic cellular massage
- Revive signature massage
What this means in practice: This program starts with a cardiovascular assessment, useful context for understanding how the body is managing stress at a systemic level, and then moves through a sequence designed to support immune function and restore energy reserves. The combination of oxygen therapy and IV immune support may help the body recover from depletion faster than passive rest alone.
Stress Management Program
Best suited for: Professionals experiencing burnout symptoms, high anxiety, or chronic tension that is not resolving through normal rest
Duration: 6 hours
What it includes:
- Brainwave monitoring
- So Check health screening
- Neurofeedback session
- Infrared sauna
- Cryotherapy
- IV therapy for stress support
- Mindful relaxation vibroacoustic session
- De-stress massage
What this means in practice: Burnout does not respond to a week off. This type of structured intervention reflects the growing shift toward preventive health optimization rather than reactive healthcare. This program works at the nervous system level using neurofeedback to help the brain shift out of chronic stress patterns, combined with physical therapies designed to lower cortisol and release muscular tension. For professionals who have been operating in a sustained fight-or-flight state, it is designed to give the body a genuine reset rather than a temporary pause.
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Package
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Duration
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Main Focus
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Best For
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Well+ Detox
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Per stay
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Detox & Recovery
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First-time guests, stress recovery
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360° Longevity
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7 hours
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Biological age & cellular health
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Executives focused on long-term performance
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Sleep Optimization
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5.5 hours
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Sleep cycles & restoration
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High-load professionals with poor sleep
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Detox Program
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4 hours
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Cellular cleansing & renewal
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Gut health, metabolic reset
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Immunity Support
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4.5 hours
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Immune system & vital energy
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Frequent travellers, post-illness recovery
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Stress Management
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6 hours
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Burnout & anxiety reduction
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Leaders managing chronic pressure
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Physical Recovery and Restoration
The recovery infrastructure at Aliée is genuinely extensive. The 4,000 sqm sanctuary includes a marble Turkish hammam, Finnish, infrared, and Russian banya (wood-fired, with traditional venik massage), and an Aufguss ritual sauna using essential oils. Cold contrast options include a multi-cryo hacking system and an ice fountain. Pools include a 30-meter-high-ceiling swimming pool with fire pits, a shorefront lagoon pool, and an Olympic lap pool, not the typical hotel add-ons.
The longevity clinic, supported by the London Regenerative Institute, offers IV therapies (NAD+, glutathione, and immune boost), bespoke regenerative cell treatments, and advanced monitoring. This is medical-grade support delivered in a hospitality environment, which is a meaningful distinction from a standard spa. It reflects the growing interest in precision wellness care focused on prevention, recovery, and long-term performance.
Mental Clarity and Stress Reduction
Neurofeedback is one of the more clinically grounded tools in Aliée's mental wellness offering. It is used in both the Sleep Optimization and Stress Management programs to help the brain shift out of overactive stress patterns. Brainwave monitoring precedes treatment in relevant programs, so the approach is informed, not generic.
Beyond technology, the property offers sound healing and tea ceremony rituals, a floating sound experience (in-water weightlessness), and a resident curator who leads curated tours of the hotel's notable Turkish art collection. These are not filler activities for many professionals; the mental decompression comes as much from cultural engagement and sensory contrast as it does from formal therapy.
Nutrition and Metabolic Health
All longevity programs that include nutrition support begin with a consultation before treatment so dietary recommendations are framed around your specific biomarkers and health screening results, not a generic meal plan. The goal is to better understand metabolic decline and recovery through personalized nutrition and health assessments.
On the dining side, Little House focuses on farm-to-table cooking. Green Corner serves plant-forward grain bowls and cold-pressed juices. The Well+ Lounge offers curated tea degustation. For those staying longer, this range makes it easier to eat in a way that supports the programs rather than undermining them.
Sleep Optimisation
Sleep is treated as a measurable outcome here, not an afterthought. The Sleep Optimization Program uses brainwave monitoring to establish a baseline, neurofeedback to work on sleep architecture, and vibroacoustic therapy, which is sound-based and delivered through the body to help shift the nervous system into deep sleep states. Rooms come with personalized pillow menus, and the overall hotel environment is designed with noise reduction and natural light management in mind.
The morning starts gently. Tuesday through Sunday, complimentary rowing sessions on the Golden Horn run from 9 to 11am, an unexpectedly grounding way to begin a day in one of the world's most densely active cities. Sunrise yoga on the lawns is the quieter alternative if you prefer stillness over movement.
After breakfast, whether that is the farm-to-table simplicity of Little House or a cold-pressed juice from Green Corner, your scheduled wellness sessions begin. Depending on your program, this might mean moving through the biohacking circuit (infrared, cryo, lymphatic flow) in the morning, followed by a consultation, then an IV session, then a longer treatment in the afternoon. The sequencing is designed so that the more intense interventions come first while your body is still fresh.
Afternoons have a looser structure. Art of Ebru water marbling workshops, art collection tours with the resident curator, or a walk through Tersane Istanbul, the cultural district that surrounds the hotel, are all available without booking far in advance. The hammam and pools are available throughout the day.
Evenings have a different energy. Sunset cocktails at the Pink Bar (18+ only) offer a whimsical contrast to the clinical focus of the day, and the bar does what good bars in Istanbul do: it pulls you into the view and gives you somewhere to exhale. On selected evenings, Mondaine de Pariso offers immersive dinners with theatrical performances.
Aliée sits directly on the waterfront of the Golden Horn in Beyoğlu, the historic site of the Ottoman imperial shipyard, previously home to the Aynalikavak Palace. The location carries genuine historical weight. The Heritage Villa, one of the hotel's most notable suites, is a 600-year-old Ottoman hammam that has been converted into private accommodation. That is not a marketing line; it is an architectural fact that changes how a stay here feels.
The setting is simultaneously private and central. The Galata Tower, Taksim Square, and the Historic Peninsula are all within easy reach. But within the property itself, the seaside gardens (Hasbahçe), the hydrangea borders, the gated pool areas, and private terraces, there is a level of seclusion that you do not usually find in a city hotel.
The property works in all seasons. Fire pits next to the pools make winter stays genuinely atmospheric — watching snow over the Golden Horn from a heated outdoor space is the kind of thing that is hard to replicate elsewhere. Summer brings the full lagoon and shorefront pool experience. If you are timing your visit, spring and autumn offer a manageable combination of good weather and lower peak-season demand.
Istanbul Airport (IST) is the closest major airport. The hotel can arrange a private driver or, more memorably, a private boat transfer directly to the waterfront dock.
Istanbul is a well-connected city, and Aliée's location in Beyoğlu puts you close to the waterway and road links to most of the city's key districts. A hire car is not necessary if you plan to stay within the hotel for most of your program; the retreat experience is self-contained enough that most guests find they do not need one.
Looking for accommodation near the retreat, or want to explore the area before or after your program?
Travelling from abroad or across the country? Check Cheap Flights
Prefer to drive at your own pace once you land? Check Car Rentals
Included:
- Complimentary morning rowing sessions on the Golden Horn (Tues–Sun, 9–11am)
- Access to the hotel's Turkish and international art collection
- Access to Nickelodeon Play! for children (family-oriented rooms)
- Sunrise yoga sessions
- Daily breakfast (in select room packages confirm at booking)
- Concierge, private driver and boat transfer arrangement (on request)
Not included:
- Longevity and wellness program fees (priced separately confirm directly with the property)
- IV therapies and clinical longevity treatments
- Dining at Taste by Aliée and Pink Bar
- Airport transfers (available but charged separately)
- Executives who are performing well on the outside but running on low reserves — and who need a structured way to rebuild, not just a break
- Founders at a high-growth stage who have not had a properly structured recovery in over a year, and whose sleep has been a casualty of that pace
- Senior managers and business owners managing chronic stress who want a clinical framework for addressing it, not just massage and meditation
- Frequent international travellers whose immune systems, sleep cycles, and energy levels have been disrupted by sustained movement across time zones
- Professionals who have tried standard wellness offerings — and are ready for something with more measurement, more precision, and more clinical backing
- Couples where one or both partners are in high-output professional roles, who want a shared retreat experience that actually addresses their health alongside the indulgence
- Solo travellers in their 40s or 50s who are starting to think seriously about longevity and want a credible starting point guided by experts, not guesswork
Many guests are also looking for long-term recovery strategies that support healthier aging and sustained energy.
Aliée Istanbul holds a 4.95/5 rating across 186 reviews, with a 9.9/10 on both Expedia and Booking.com and a perfect 10/10 on TripAdvisor. Guest feedback consistently highlights the art collection, the preserved shipyard architecture, and the quality of the wellness staff.
Individual experiences vary. Results depend on personal health, program selection, and level of engagement.
- Featured in Global Traveler, 2025
- Featured in Hospitality Net
- Part of the Paris Society Hotel Collection
- Managed by Ennismore, in joint venture with Accor
Is this retreat suitable if I have never done anything like this before?
Yes. The wellness team is experienced in guiding first-time guests through the programs, and the Well+ Detox package is specifically structured as an accessible entry point. Rowing sessions and yoga classes are expert-guided for all fitness levels. You do not need any prior experience with biohacking, IV therapy, or advanced recovery technology.
Can I attend on my own?
Absolutely. Solo travellers are a recognised guest profile at Aliée, and the retreat experience is fully self-contained. You will have access to guided activities, a curated cultural program, and individual wellness sessions without any need for a travel companion.
How long do I need to stay to notice a difference?
The minimum stay is 2 nights, but the property recommends longer for full program benefit. Intensive single-day programs like the 360° Longevity or Stress Management can be completed within a 2 to 3 night stay. For sleep reprogramming or more gradual cellular work, a 5 to 7 night stay allows the therapies to build on each other rather than deliver a single input.
Does extendmy.life book the retreat directly?
No. extendmy.life is a curated platform. When you click to book, you are taken directly to the retreat provider's own booking system. extendmy.life may receive a referral fee for qualifying bookings. This does not affect your price.
What is the difference between the 360° Longevity Program and the other packages?
The 360° Longevity Program is the most comprehensive single-day offering. It combines a full health assessment, longevity consultation, biohacking circuit, NAD+ IV infusion, neurofeedback, and physical treatment all in one structured day. The other programs (Sleep, Detox, Immunity, Stress) are more targeted. They address a specific system or outcome rather than providing an overall biological audit. If you are unsure where to start, the 360° program gives you and the clinical team the most information to work with.
Are the wellness programs suitable if I have an existing health condition?
Some treatments including IV therapies, cryotherapy, and neurofeedback may not be appropriate for all medical conditions. The longevity clinic team, supported by the London Regenerative Institute, conducts health screenings before treatment as part of the programs. That said, if you have a known condition, speak with your own healthcare provider before booking and inform the retreat team at the time of inquiry so they can advise accordingly.
Can my partner join me if they want a different program?
Yes. Programs can be selected independently. Some treatments in the Well+ Detox package can also be shared between guests or divided across the stay. Couples often use Aliée as a joint retreat with different program focuses running in parallel, one partner on sleep optimization and the other on stress management, for example.
Are there any age restrictions?
The Pink Bar and Taste by Aliée restaurant are both 18+ only. The hotel welcomes families and has Nickelodeon Play! for children. Photography and videography are restricted across the property, allowed only in the living room to protect guest privacy.
You apply careful thinking to most of the important decisions in your professional life. The way you allocate time, manage risk, and maintain output under pressure. Your health deserves the same level of intention, and Aliée Istanbul is one of the few places that treats it that way.
You do not need more downtime. You need better recovery that is structured, measured, and built around what your body actually needs.
Book your retreat at Aliée Istanbul
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Disclaimer
extendmy.life may earn a referral fee if you book through links on this page. This does not affect our editorial recommendations or the price you pay. All prices shown on this page are indicative and subject to change without notice. Always confirm current rates directly with the retreat provider before booking. This page is for informational purposes only. extendmy.life is not a medical provider and does not offer medical advice, diagnosis, or treatment. The retreat programs described here are wellness experiences, not medical treatments. If you have an existing health condition or are unsure whether a retreat program is right for you, please speak with a qualified healthcare professional before booking.